Biography:

Dr. Sager is Director of the Wisconsin Alzheimer’s Institute and a Professor of Medicine at the University of Wisconsin-Madison School of Medicine and Public Health. He is the founder of the Wisconsin Registry for Alzheimer’s Prevention (WRAP) which is a longitudinal study of adult children of persons with Alzheimer’s disease. The primary goal of WRAP is to conduct genetic, epidemiological and clinical research that could lead to the prevention of Alzheimer’s disease. Dr. Sager also developed the WAI affiliated network of dementia diagnostic clinics consisting of Wisconsin physicians and health care providers dedicated to improving the care provided to persons with Alzheimer’s disease and their families. He is a fellowship trained geriatrician and received his MD from the University of Michigan. Dr. Sager joined the UW faculty in 1992.

Publications:

• Midlife measurements of white matter microstructure predict subsequent regional white matter atrophy in healthy adults

  April 3, 2013

• Cerebral blood flow is diminished in asymptomatic middle-aged adults with maternal history of Alzheimer’s disease

  January 1, 2013

• Low cerebral blood flow is associated with lower memory function in metabolic syndrome.

  January 1, 2013

• Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults

  August 1, 2012

• Family history of Alzheimer disease predicts hippocampal atrophy in healthy middle-aged adults

  February 1, 2012

• Medial Prefrontal Functional Connectivity - Relation to Memory Self-appraisal Accuracy in Older Adults with and without Memory Disorders

  January 1, 2012

• The Effects of Ramipril in Individuals at Risk for Alzheimer's Disease: Results of a Pilot Clinical Trial

  January 1, 2012

• Effects of Atorvastatin on Cerebral Blood Flow in Middle-Aged Adults at Risk for Alzheimer's Disease: A Pilot Study

  January 1, 2012

• The Effect of TOMM40 Poly-T length on Gray Matter Volume and Cognition in Middle-Aged Persons with APOE ε3/ε3 Genotype

  March 1, 2011

• NSAIDs may protect against age-related brain atrophy

  September 3, 2010

• White matter is altered with parental family history of Alzheimer’s disease

  September 1, 2010

• Low HDL cholesterol is associated with lower gray matter volume in cognitively healthy adults

  July 15, 2010

• The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memory

  February 1, 2009