The research of my group is focused on developing imaging and analysis techniques for the study of human brain function with magnetic resonance imaging (MRI) at 3 tesla. My research group is actively involved in the following research areas:
- Functional MRI Techniques. We are developing and evaluating methods for improving the robust characterization of the BOLD effect in functional brain studies. Of particular interest are developing methods for imaging areas with susceptibility artifacts (e.g., the orbitofrontal cortex, and the temporal lobes).
- Functional MRI of TMS Brain Stimulation. We are developing methods to measure the BOLD activity response to transcranial magnetic stimulation.Diffusion Tensor MRI. We are developing acquisition, processing and display algorithms for accurate characterization of brain diffusion properties. These measurements provide unique information about brain tissue microstructure.
- White Matter Organization Mapping. We are developing methods using diffusion tensor imaging to map out the organization of white matter connections within the brain.
- Structural Characterization of Brain Tissues. We are using diffusion, magnetization transfer and spectoscopic techniques to evaluate structural properties of brain tissues (e.g., myelination, axon density, brain development, etc.). These techniques may be used to assess structural changes as a function of either brain disfunction or normal brain development.